cGMP Facility • Texas
(844)-323-5628
Supplements Manufacturing

Liquid Manufacturing & Tinctures

Aqueous, oil-based, and nano-emulsified liquid supplement manufacturing with aseptic-grade filling.

MNL manufactures oral liquid supplement formats including sublingual drops, wellness tinctures, functional syrups, and liposomal nano-emulsified delivery systems. Our stainless steel liquid processing suites are equipped for cold-process and heat-process formulation, with homogenization and microfluidization capability for nano-emulsion particle sizing. All liquid fills are conducted in humidity- and temperature-controlled filling rooms.

Request a Production QuoteConsult Technical Team

Supported Dosage Forms & Formats

Sublingual Tinctures (dropper bottle, 1–2 oz)Oral Syrups & Elixirs (flavored aqueous formulas)Liposomal Nano-Emulsions (fat-soluble actives in aqueous base)Oil-Based Supplements (MCT, fish oil, hemp extract in oil)Liquid Minerals & Ionic Trace Mineral FormulasFunctional Wellness Shots (2 oz liquid dietary supplement)RTD Beverage Base Concentrates

Quick Fact Sheet

Key production parameters

Minimum Order Quantity

500 units

Standard Lead Time

4–6 weeks from formula approval and PO

Cleanroom Standard

ISO Class 8 liquid filling suite / 21 CFR Part 111 cGMP

Packaging Compatibility

  • Glass Dropper Bottles (1 oz / 2 oz, amber or cobalt)
  • HDPE or PET Screw-Cap Bottles (4 oz – 32 oz)
  • Aluminum Sealed Pouches (travel single-dose)
  • Plastic Dropper Bottles (LDPE, natural or amber)
  • Glass Amber Bottles with tamper-evident cap
  • 2 oz Wellness Shot Bottles (glass or PET)

Mutual NDA Standard: All formula details, BOM data, and brand concepts shared during the quoting process are protected under a reciprocal Non-Disclosure Agreement executed before technical evaluation begins.

Laboratory Asset Pipeline

Machinery & Specimen Visual Verification

Inspect actual cleanroom machinery, finished dosage macro specimens, and packaging protocols dedicated to liquid manufacturing & tinctures.

Amber dropper bottle dispensing single golden tincture drop
Specimen Macro
Particle Size: 50-150 nm | Conductivity < 1.3 µS/cm

Sublingual Nano-Emulsion Drops

USP purified water and organic MCT carrier tinctures formulated with micellar lipid technology.

Automated liquid peristaltic filling lines with nitrogen purge
Machinery Suite
Fill Range: 10mL - 1,000mL | Inline Nitrogen Purge

Sanitary Liquid Compounding & Multi-Head Filling

High-accuracy positive displacement filling nozzles with automated inert nitrogen head-space flushing.

Analytical chemist running HPLC chromatography testing on liquid batch
Packaging & QA
HPLC UV-Vis Assay | ICP-MS Heavy Metal Testing

Analytical Potency & Heavy Metal Testing (HPLC / ICP-MS)

Active potency verification and parts-per-billion heavy metal screening on every liquid lot.

Engineering Specification Table

ParameterSpecification / ValueNote
Minimum Batch Size
50 liters (pilot); 500 liters (commercial)
MNL SPEC
pH Control Range
pH 3.0 – 8.5 (aqueous formulas)
MNL SPEC
Nano-emulsion Particle Size
< 200 nm (D90) by dynamic light scattering
MNL SPEC
Viscosity Range
1 – 50,000 cPs (Newtonian to non-Newtonian)
MNL SPEC
Fill Volume Accuracy
±1% of target fill volume
MNL SPEC
Filling Speed (automated line)
Up to 1,800 units/hour (30 mL fills)
MNL SPEC
Preservative Systems
Benzyl alcohol, potassium sorbate, citric acid (formula-specific)
MNL SPEC
Processing Temperature
Cold-process (ambient) and heat-process (up to 80°C)
MNL SPEC
Cleanroom Classification
ISO Class 8 liquid filling suite / 21 CFR Part 111
MNL SPEC
Standard Batch Lead Time
4–6 weeks from formula lock and PO
MNL SPEC

Specifications are representative of standard production parameters. Project-specific values may vary based on formula requirements, ingredient characteristics, and target packaging format. Contact our engineering team for exact specifications relevant to your batch.

Quality Assurance & Verification Protocol

Every liquid manufacturing & tinctures batch passes through a four-phase analytical verification workflow before Certificate of Analysis issuance and release.

01

Raw Material & Solvent QC

All liquid raw materials, botanical extracts, and solvent bases (water, ethanol, MCT, glycerin) confirmed for identity and purity. Water purified per USP Purified Water specification.

Raw material COA verificationPurified water testing (conductivity, endotoxin, microbial)Botanical extract identity (HPLC, TLC)Ethanol / solvent purity (GC headspace)
02

In-Process Formulation Controls

pH, appearance, and specific gravity measured at each blending phase. For nano-emulsions, particle size distribution confirmed by dynamic light scattering (DLS) before filling.

pH measurement (digital pH meter, calibrated)Appearance / clarity / color visual inspectionSpecific gravity (pycnometer)Nano-emulsion particle size (DLS, < 200 nm target)Viscosity (Brookfield rheometer)
03

Finished Liquid Product Testing

Potency, microbial, and physical testing on finished bulk before filling, and retained finished-container samples after filling. Fill volume accuracy confirmed per lot.

Label claim potency (HPLC, UV-Vis)Microbial limits (TPC, yeast & mold, Salmonella, E. coli)Fill volume accuracy check (10-unit sample)Preservative efficacy (USP <51> antimicrobial effectiveness, if applicable)Heavy metals screen (ICP-MS)
04

COA Release

QA Director reviews batch record, all analytical results, and filling run data. COA issued with pH, assay, fill volume, and microbial results. Stability program recommended for all liquid SKUs.

QA Director batch record reviewCOA issuance with full test panelContainer closure integrity confirmationStability program enrollment (accelerated + real-time)

Certificate of Analysis (COA) — Issued Per Batch

Every commercial batch receives a QA Director–signed Certificate of Analysis on MNL letterhead. The COA documents all test parameters, analytical methods, results versus specification, and full lot traceability to raw material COAs. No batch ships without COA authorization.

Production Specification Request

Request a Quote for Liquid Manufacturing & Tinctures

Submit your project brief through our structured multi-step quote engine. Pre-select Liquid Manufacturing & Tinctures as your target manufacturing service. Our Carrollton, TX formulation and production team will provide a preliminary feasibility response within 24–48 business hours, under mutual NDA before any formula details are exchanged.

  • Preliminary quote returned within 24–48 business hours
  • Mutual NDA executed before formula review
  • Direct access to MNL formulation chemists
Request Quote for Liquid Manufacturing & Tinctures

Or contact our engineering team directly

(844)-323-5628info@micellecosmeticslabs.com

Mon – Fri: 8:00 AM – 5:00 PM CST. Facility visits by advance appointment.

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